Introduction: Obsessive compulsive disorder with chronic course, heterogeneity in symptoms and resistance to change as well as one of the most debilitating anxiety disorders, it’s necessary the need for increasingly to investigation of multidimensional nature of pathology, complex and transdiagnostic. Accordingly, the aim of this study was to investigate the contribution of transdiagnostic processes such as intolerance of uncertainty, cognitive fusion and distress intolerance to prediction of obsessive compulsive disorder in clinical population.


Method: In correlation- cross sectional current study, 155 subjects with obsessive compulsive disorder referred to clinics Roozbeh Psychiatric Hospital, Ayatollah Taleghani Hospital (department of psychiatry) and Iran Psychiatric Hospital, selected by available sampling method and completed Obsessive Compulsive Inventory– Revised (OCI-R), Intolerance Uncertainty Scale (IUS), Distress Tolerance Scale (DTS) and Cognitive Fusion Questionnaire (CFQ). The gathered data was analyzed using Pearson correlation and multiple regression.


Results: The results showed that intolerance of uncertainty, cognitive fusion and intolerance distress were correlated with the Obsessive compulsive disorder. Based on regression analysis, the variables are generally able to predict 69% of the variance in obsessive-compulsive disorder, among which, the role of predicted of cognitive fusion was higher than other variables.


Conclusion: According to the findings of this study, transdiagnostic constructs, such as intolerance of uncertainty, cognitive fusion and distress intolerance able to predict obsessive-compulsive disorder and this finding may be an important step in the advancement and development of transdiagnostic protocols be considered in the treatment of this disorder.