Clinical Psychology and Personality

Clinical Psychology and Personality

Introduction and use of techniques based on memetic psychology in the treatment of major depressive disorder: A qualitative case study

Document Type : Original Article

Authors
1 Psychology Postdoctoral researcher, Department of Psychology, Razi University, Kermanshah, Iran.
2 Associate Professor Professor, Department of Psychology, Razi University, Kermanshah, Iran .
Abstract
Introduction: Major depression is one of the disorders that can severely affect the patient's quality of life and in the worst case can cause suicidal thoughts in the patient and even suicide attempts. Therefore, the aim of the present study was to introduce techniques based on memetic psychology and examine their effect on major depressive disorder.
Method: The present study was a qualitative case study. The statistical population of this study consisted of all people diagnosed with major depressive disorder living in Kermanshah in 2024. To select the research sample, a purposive sampling method was used and one subject diagnosed with major depressive disorder was selected using a diagnostic interview based on DSM-5. The participant underwent memetic psychology-based interventions for 10 weeks.
Results: Finally, the use of the diagnostic interview based on DSM-5, Beck Depression Inventory-2, researcher observations, and patient self-report showed that the use of techniques based on memetic psychology, including Mapping the self, Meme maps, and Deconstructing Memes, is effective in treating major depressive disorder.
Discussion and conclusion: The results of this study showed that memetic psychology, as a sub-branch of cultural evolution, can have appropriate explanatory power in how mental disorders arise and persist. Therefore, given the positive effect of techniques based on memetic psychology in the present study, this study was able to create a basis for developing protocols based on memetic psychology in the future.
Keywords

1-    Herrman, H., Kieling, C., McGorry, P., Horton, R., Sargent J, Patel V. Reducing the global burden of depression: a lancet – world psychiatric association commission. The Lancet. 2019 Jun 15. https://doi.org/10.1016/S0140-6736(18)32408-5
2-    World Health Organization. Depression (Fact Sheet). WHO: Geneva, Switzerland. 2020; Available online: (accessed on 1 December 2022).
3-    Herrman, H,. Patel, V., Kieling, C., Berk, M., Buchweitz, C., Cuijpers, P., et al. Time for united action on depression: a Lancet–World Psychiatric Association Commission. The Lancet. 2022 Mar 5; 399(10328): 957-1022. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02141-3/abstract
4-    Goldberg, J. F., Nasrallah, H. A. Major depression is a serious and potentially fatal brain syndrome requiring pharmacotherapy or neuromodulation, and psychotherapy. Psychological Medicine. 2022 Jun; 52(8):1423-5. https://doi.org/10.1017/S0033291722001179
5-    Reynolds 3rd, C. F., Jeste,  D. V., Sachdev, P. S., Blazer, D.G. Mental health care for older adults: recent advances and new directions in clinical practice and research. World Psychiatry. 2022 Oct; 21(3): 336-63. https://doi.org/10.1002/wps.20996
6-    Pérez-Sola, V., Roca, M., Alonso, J., Gabilondo, A., Hernando, T., Sicras-Mainar, A., et al. Economic impact of treatment-resistant depression: a retrospective observational study. Journal of Affective Disorders. 2021 Dec 1; 295: 578-86. https://doi.org/10.1016/j.jad.2021.08.036
7-    Lin, C., Huang, C. M., Karim, H. T., Liu, H. L., Lee, T. M., Wu, C. W., et al. Greater white matter hyperintensities and the association with executive function in suicide attempters with late-life depression. Neurobiology of aging. 2021 Jul 1; 103:60-7. https://doi.org/10.1016/j.neurobiolaging.2020.12.016
8-    Mayor, S. Persistent depression doubles stroke risk despite treatment, study finds. BMJ. 2015 May 15;350. https://doi.org/10.1136/bmj.h2611
9-    Huang, C. M., Fan, Y. T., Lee, SH, Liu, H. L., Chen, Y. L., Lin, C., et al. Cognitive reserve-mediated neural modulation of emotional control and regulation in people with late-life depression. Social cognitive and affective neuroscience. 2019 Aug;14(8):849-60.  https://doi.org/10.1093/scan/nsz054
10- Park, E. H., Jung, M. H. The impact of major depressive disorder on adaptive function: A retrospective observational study. Medicine. 2019 Dec 1; 98(52): e18515https://doi.org/ 10.1097/MD.0000000000018515
11- Nock, M. K., Hwang, I., Sampson, N., Kessler, R. C., Angermeyer, M., Beautrais, A., et al. Cross-national analysis of the associations among mental disorders and suicidal behavior: findings from the WHO World Mental Health Surveys. PLoS medicine. 2009 Aug 11; 6(8): e1000123. https://doi.org/10.1371/journal.pmed.1000123
12-  Chiao, J. Y., Blizinsky, K. D. Culture–gene coevolution of individualism–collectivism and the serotonin transporter gene. Proceedings of the Royal Society B: Biological Sciences. 2010 Feb 22; 277(1681): 529-37. https://doi.org/10.1098/rspb.2009.1650
13- Khatami, M. Introduction to Memetic Philosophy. Scientific Civilization Publications. Tehran, Iran; 2018. [In Persian]
14- Safron, A. Multilevel evolutionary developmental optimization (MEDO): A theoretical framework for understanding preferences and selection dynamics. arXiv preprint arXiv: 1910.13443. 2019 Oct 27.
https://doi.org/10.48550/arXiv.1910.13443
15- Russell, C. J., Muthukrishna, M. Dual inheritance theory. InEncyclopedia of evolutionary psychological science 2021 Apr 22 (pp. 2140-2146). Cham: Springer International Publishing. https://doi.org/10.1007/978-3-319-19650-3_1381
16- Dawkins, R. The selfish gene. Oxford university press; 2016.
17- Beattie, P., Beattie, P. Information: Evolution, psychology, and politics. Social Evolution, Political Psychology, and the Media in Democracy: The Invisible Hand in the US Marketplace of Ideas. 2019: 17-61. https://link.springer.com/book/10.1007/978-3-030-02801-5
18- Whiten, A., Ayala, F. J., Feldman, M. W., Laland, K.N. The extension of biology through culture. Proceedings of the National Academy of Sciences. 2017 Jul 25; 114(30): 7775-81. https://doi.org/10.1073/pnas.1707630114
19- Blackmore, S. Memetics does provide a useful way of understanding cultural evolution. Contemporary debates in philosophy of biology. 2010: 255-72. https://doi.org/10.1002/9781444314922.ch
20- Brodie, R. Virus of the mind: The new science of the meme. Hay House, Inc; 2009 May 15. https://www.google.com/books/edition/Virus_of_the_Mind/ioBbmPrmujsC?hl=en&gbpv=1&dq=20-+Brodie+R.+Virus+of+the+mind:+The+new+science+of+the+meme.+Hay+House,+Inc%3B+2009+May+15.&pg=PR13&printsec=frontcover
21- Leigh, H. Genes, memes, culture, and mental illness: Toward an integrative model. Springer Science & Business Media; 2010 Jun 14. https://escholarship.org/content/qt5gj3v3rn/qt5gj3v3rn_noSplash_1776ae2e60474219353dbb93b417be9c.pdf
22- Blackmore, S. J. The meme machine. Oxford Paperbacks; 2000 Mar 16. https://www.google.com/books/edition/The_Meme_Machine/YKtjZm4MhiwC?hl=en&gbpv=1
23- Distin, K. The selfish meme: A critical reassessment. Cambridge University Press; 2005. https://www.google.com/books/edition/The_Selfish_Meme/NKvz4r5sIDAC?hl=en&gbpv=1&dq=23-+Distin+K.+The+selfish+meme:+A+critical+reassessment.+Cambridge+University+Press%3B+2005.&pg=PA1&printsec=frontcover
24- Robertson, L. H. Mapping the self with units of culture. Psychology. 2010 Aug 25; 1(03): 185. https://doi.org/10.4236/psych.2010.13025
25- Robertson, L. H. Self-mapping in treating suicide ideation: A case study. Death Studies. 2011 Mar 9; 35(3): 267-80. https://doi.org/10.1080/07481187.2010.496687
26- Robertson, L. H. Self-mapping in counselling: Using memetic maps to enhance client reflectivity and therapeutic efficacy. Canadian Journal of Counselling and Psychotherapy. 2016 Jul 18; 50(3). https://cjc-rcc.ucalgary.ca/article/view/61110
27- Paull, J. Meme maps: A tool for configuring memes in time and space. European Journal of Scientific Research. 2009; 31(1): 11-8. https://orgprints.org/id/eprint/15752/
28- Dovanloo, H. Short-term dynamic psychotherapy. Creative translation by Sigarudi, Enayat. Arjomand Publications. Tehran. Iran; (2024). [In Persian]
29- Mohamadpour, S.‌, Tajikzadeh, F., Mohamadi, N. The efficacy of mindfulness-based cognitive therapy on Depression, Rumination and Dysfunctional Attitude in Pregnant women with depression, Biannual Peer Review Journal of Clinical Psychology & Personality. 2018; 16(1): 187-198. magiran.com/p1894852 [In Persian]
30- Melyani, M., Alahyari, A. A., Azadfallah, P., Fathi Ashtiani, A., Tavoli, A. Miulness based Cognitive therapy versus Cognitive Behavioral therapy on predictors of relapse in recurent Depression, Biannual Peer Review Journal of Clinical Psychology & Personality2014; 12(1): 75-86. magiran.com/p2127873  [In Persian]
31- Devers, K. J., Frankel, R. M. Study design in qualitative research—2: Sampling and data collection strategies. Education for health. 2000 May 1; 13(2): 263-71. file:///C:/Users/User-01/Downloads/study_design_in_qualitative_research_2__sampling.15.pdf
32- Martin, C. S., Pollock, N. K., Bukstein, O. G., Lynch, K. G. Inter-rater reliability of the SCID alcohol and substance use disorders section among adolescents. Drug and alcohol dependence. 2000 May 1; 59(2): 173-6. https://doi.org/10.1016/S0376-8716(99)00119-2
33- Sharifi, V., Asadi, S. M., Mohammadi. M. R., Amini, H., Kaviani, H., Semnani, Y., et al. Reliability and feasibility of the Persian version of the Scientific Diagnostic Interview for SCID). Quarterly Journal of Cognitive Sciences. 2004; 6(1): 10. magiran.com/p320768 [In Persian]34. Beck, A. T., Steer, R. A., Brown, G. Beck depression inventory–II. Psychological assessment. 1996 Jan 1. https://doi.org/10.1037/t00742-000
34- Dabson, K, S., Mohammad khani, P. Psychometrics Characteristic of Beck Depression Inventory-II in Patients with Magor Depressive Disorder, Archives of Rehabilitation. 2007; 8(1): 82. magiran.com/p459529 [In Persian]